Target indications
Serving Unmet Needs
$15.8B
Combined Treatment Market Size
Cognos is at the forefront of developing innovative treatments addressing Alzheimer’s and various types of cancer. Alzheimer’s disease, affecting over 50 million people globally, including 6.9 million in the U.S., represents a significant challenge due to the difficulty of drug delivery to the brain and the economic burden of $340 billion annually.
180K
Total Addressable Market (TAM)
The company’s brain microdialysis technology is positioned to enable the first streamlined treatment for Alzheimer’s, overcoming the blood-brain barrier and creating substantial potential for market leadership. In addition to Alzheimer’s, Cognos is tackling unmet needs in the treatment of central nervous system (CNS) diseases and multiple neurological cancers, including Leptomeningeal carcinomatosis (LC), glioblastoma (GBM), and pancreatic cancer. The SINNAIS™ AI smart drug delivery implantable pump is designed to address these critical areas.
The total U.S. addressable market for SINNAIS™ is at least 180,000 patient cases per year, based on estimated annual diagnoses of 110,000 for LC, 60,000 for pancreatic cancer, and 12,000 for glioblastoma. LC cases associated with breast cancer, melanoma, and lung cancer comprise over 50% of the target population.
The combined treatment market for these cancer diagnoses in the U.S. is estimated to be approximately $15.8 billion per year, including $6 billion for LC, $8 billion for pancreatic cancer, and $1.8 billion for glioblastoma. With this multi-faceted approach, Cognos is poised to capture significant opportunities and address critical gaps in both neurodegenerative and cancer treatment markets.
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